AMP stands for Antibody Mediated Prevention. This is the idea of giving people antibodies to see if they will protect against HIV infection.

This study, also referred to as HVTN 703/HPTN 081, tests a new idea for HIV prevention. In traditional vaccine studies, we give people a vaccine and wait to see if their bodies will make antibodies against HIV in response. In this study, we’ll be skipping that step, and just giving people the antibodies directly. We will do this through an infusion, which some people know better as getting an IV or getting a drip. This is the first study testing whether this antibody can prevent HIV infections in people.